Comments on: How many people ever lived? http://talaya.net/chronicles/how-many-people-ever-lived/ Notes for a new book by George Johnson Tue, 28 May 2013 00:10:37 +0000 hourly 1 By: George Johnson http://talaya.net/chronicles/how-many-people-ever-lived/#comment-9 Wed, 19 Jan 2011 17:51:31 +0000 http://talaya.net/chronicles/?p=59#comment-9 Kendall,
I’m glad to have you as a reader. From what I have learned so far, some cancers are more likely to metastasize than others and each tends to seek out different targets. Breast and prostate cancer have a propensity for bone. Ovarian and colon cancer rarely go there. For carcinomas in general, the lung and liver are the most likely target for metastasis. Bone is third. Whether any cancer that didn’t kill its host would eventually end up in the skeleton is something I do not know.

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By: George Johnson http://talaya.net/chronicles/how-many-people-ever-lived/#comment-8 Wed, 19 Jan 2011 17:38:09 +0000 http://talaya.net/chronicles/?p=59#comment-8 Dwayne,

You have put your finger on one of the mysteries I’ll be grappling with in the book. In developed countries with reasonably competent record-keeping, changes in the incidence of different kinds of cancers can be plotted. And even then the causation is controversial — how much is from early detection and how much from diet, exposure to carcinogens, etc.? When you look back even a century, death records become much less reliable — and cancer was considered a stigma so another cause of death was often listed. Go back even further and you are relying on scant historical records and the archaeological ambiguities I wrote about in the article.

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By: Kendall Powell http://talaya.net/chronicles/how-many-people-ever-lived/#comment-7 Wed, 19 Jan 2011 16:38:44 +0000 http://talaya.net/chronicles/?p=59#comment-7 Hi George,
I am slow to get around to reading, but both this post and your Times article made me ponder a medical question…does all cancer (if left untreated) eventually metastasize to and show up in bones?

Also, what about animal skeletons? Must be many more of them unearthed, right? If Weinburg’s idea about multicellular life holds true, then shouldn’t we also be able to track it in animal remains? Or do most animals die from predation before cancer would have had time to kick in?

Clearly, you’ve got me interested…

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By: Dwayne Stephenson http://talaya.net/chronicles/how-many-people-ever-lived/#comment-6 Wed, 19 Jan 2011 02:03:15 +0000 http://talaya.net/chronicles/?p=59#comment-6 I’m biased against the industrialization argument, so this leads me to want to turn the question on its head: without accurate data on historical cancer rates, how could anyone even know that they’ve increased, let alone the reason why?

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